Research
Publications
Every paper and preprint by the lab's members, from their time in the lab.
743 publications1992 to 202689 preprintsBibTeX of allAtom feed
| Series | Total works | By year from 2012 |
|---|---|---|
| Component analysis and signal separation | 25 | 6, 2, 3, 5, 0, 1, 0, 0, 2, 2, 0, 0, 1, 1, 2 |
| Networks and graphs | 38 | 3, 6, 2, 7, 3, 3, 0, 2, 0, 2, 3, 3, 1, 2, 1 |
| Mechanistic modelling | 52 | 5, 8, 2, 7, 9, 6, 6, 1, 1, 1, 1, 2, 1, 1, 1 |
| Bulk omics and genetics | 131 | 8, 8, 9, 10, 19, 8, 13, 10, 4, 10, 8, 8, 2, 3, 11 |
| Statistical inference | 90 | 8, 7, 8, 13, 9, 9, 7, 5, 1, 5, 4, 5, 3, 2, 4 |
| Metabolism and diabetes | 66 | 8, 3, 5, 5, 5, 4, 3, 6, 5, 6, 5, 3, 0, 4, 4 |
| Gene regulation | 107 | 4, 6, 7, 11, 11, 4, 5, 10, 5, 7, 9, 3, 7, 8, 10 |
| Clinical and cohort data | 85 | 8, 5, 6, 5, 8, 5, 5, 7, 3, 8, 4, 10, 4, 1, 6 |
| Imaging | 70 | 1, 4, 1, 3, 8, 7, 4, 3, 6, 6, 4, 8, 6, 6, 3 |
| Cell fate and dynamics | 139 | 4, 4, 6, 15, 7, 5, 7, 10, 9, 10, 12, 10, 12, 14, 14 |
| Perturbation responses | 150 | 1, 2, 5, 10, 11, 6, 11, 6, 12, 11, 20, 15, 12, 11, 17 |
| Immunity and inflammation | 135 | 4, 2, 3, 4, 12, 8, 7, 10, 9, 14, 16, 15, 11, 8, 12 |
| Open-source software | 107 | 0, 4, 3, 5, 10, 7, 6, 4, 8, 11, 5, 8, 11, 14, 11 |
| Brain and mental health | 66 | 2, 4, 3, 4, 1, 5, 2, 4, 2, 3, 10, 3, 6, 7, 10 |
| Benchmarks and best practices | 43 | 1, 1, 1, 0, 1, 2, 3, 4, 1, 5, 3, 4, 2, 9, 6 |
| Single-cell genomics | 256 | 1, 1, 4, 6, 1, 6, 7, 19, 20, 27, 27, 29, 31, 40, 37 |
| Data integration | 117 | 1, 2, 3, 4, 2, 2, 3, 6, 4, 7, 10, 11, 19, 22, 21 |
| Deep learning and generative models | 92 | 0, 0, 0, 0, 0, 2, 1, 8, 9, 6, 5, 11, 11, 21, 18 |
| Cell atlases | 45 | 0, 0, 0, 0, 0, 1, 1, 4, 1, 2, 5, 8, 7, 7, 9 |
| Spatial omics | 62 | 0, 0, 0, 0, 0, 0, 0, 1, 0, 2, 9, 5, 12, 21, 12 |
202657 publications
Topic: Metabolism and diabetes Topic: Brain and mental healthIntegrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in MAPT V337M neurons
Topic: Cell atlasesThe Human Gut Cell Atlas v1.0: A Unified, Community-Built Reference of Cellular Diversity Across the Gut
Topic: Cell fate and dynamicsGenerative inverse design steers human hematopoietic cell fate in vitro
Topic: Data integrationArchMap is a web-based platform for reference-based analysis of single-cell datasets
Topic: Cell atlasesA Community-Driven Single-Cell PBMC Reference Integrating Landmark Datasets Spanning Health and Disease
Topic: Single-cell genomicsConvexGating infers gating strategies from clusters in single cell cytometry data
Topic: Perturbation responsesAI Scientists for Building Virtual-Cell Models
Topic: Clinical and cohort dataTime-resolved predictability of end-of-therapy outcome and relapse after cure in Phase 3 tuberculosis trials
Topic: Open-source softwareAlphaPeptTools: scverse-native analysis of mass spectrometry-based proteomics
Topic: Immunity and inflammationMultimodal discovery of a pathogenic B-cell-dependent T-cell state in multiple sclerosis
Topic: Data integrationTowards 3D-oid models that integrate molecular, morphological and spatial cellular features
Topic: Deep learning and generative modelsCreating bottom-up RNA transfer vehicles from synthetic protein assemblies
Topic: Deep learning and generative modelsDesigning antimicrobials with programmable mechanism and safety
Topic: Deep learning and generative modelsG2T: Tissue Reconstruction from Gene Expression via Embedding-Distance Flow Matching
Topic: Deep learning and generative modelsLearning Discrete Cell and Niche Codes from Spatial Transcriptomics Using Dual Residual Vector Quantization
Topic: Open-source softwareArchMap
Topic: Immunity and inflammationChemokine Landscapes of the Tumor Microenvironment
Topic: Brain and mental healthPlasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease
Topic: Spatial omicsMulti-scale modeling of human tissues from spatial transcriptomics with TERRA
Topic: Cell atlasesBuilding optimized single-cell reference atlases with scAtlasTb
Topic: Metabolism and diabetesType 2 diabetes prevention across the life course
Topic: Deep learning and generative modelsAn interpretable omnigenic neural network architecture for the human genome
Topic: Spatial omicsSpatioTemporal Omics Consortium: a global effort for biological discovery across species, space and time
Topic: Clinical and cohort dataLearning the shared structure of human health across diseases, modalities, and time
Topic: Bulk omics and geneticsRectangle: robust and scalable multiscale deconvolution informed by single-cell RNA sequencing data
Topic: Data integrationNetworkVI: Biologically Guided Variational Inference for Interpretable Multimodal Single-Cell Integration and Discovery
Topic: Immunity and inflammationMultimodal temporal mapping of macrophage transcriptome remodeling during Salmonella infection
Topic: Gene regulationTranscriptional repression by TGIF2 coordinates neurogenic priming and neural stem cell maintenance
Topic: Benchmarks and best practicesBenchmarking gene expression reconstruction from single-cell latent representations
Topic: Deep learning and generative modelsCellpin enables reference-based imputation and denoising of spatial transcriptomes
Topic: Cell fate and dynamicsRegVelo: Gene-regulatory-informed dynamics of single cells
Topic: Deep learning and generative modelsUniversalEPI: robust prediction of cell type-specific and differential chromatin interactions from DNA sequence and chromatin accessibility
Source Data Li et al Science Advances 2026
Topic: Deep learning and generative modelsInterScale reveals multi-scale cellular interaction programs in spatial transcriptomics
Topic: Deep learning and generative modelsTarDis: Achieving robust and structured disentanglement of multiple covariates
Topic: Statistical inferenceContinuous multi-omics pathway enrichment analysis resolves hidden functional heterogeneity
Topic: Spatial omicsPan-cancer virtual spatial transcriptomics from routine histology with Phoenix
Topic: Cell fate and dynamicsNon-destructive transcriptomics via vesicular export
Topic: Brain and mental healthTNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation
Topic: Cell atlasesAn integrated single cell and spatial omics atlas of human prenatal development
Topic: Bulk omics and geneticsLarge-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis
Topic: Cell atlasesPerturbation-guided mapping of colorectal cancer cell states to causal mechanisms
Topic: Benchmarks and best practicesCP-BG-1M: A CONTROLLED MULTI-VIEW BENCH- MARK FOR DENSITY AND BACKGROUND SHORTCUTS IN MORPHOLOGY PROFILING
Topic: Cell fate and dynamicsGenerative models of cell dynamics: from Neural ODEs to flow matching
Topic: Benchmarks and best practicesLongitudinal modality prediction learns gene regulatory patterns: insights from a single-cell competition
Topic: Data integrationBeyond alignment: synergistic integration is required for multimodal cell foundation models
Topic: Spatial omicsIdentifying 3D signal overlaps in spatial transcriptomics data with ovrlpy
Topic: Open-source softwareIDTrack: Time- and Namespace-Aware Identifier Harmonization for Reproducible Workflows
Topic: Deep learning and generative modelsFrom modality-specific to compositional foundation models for cell biology
Topic: Cell fate and dynamicsCellRank: consistent and data view agnostic fate mapping for single-cell genomics
Topic: Cell atlasesSingle-cell atlas of the transcriptome and chromatin accessibility in the human retina
Topic: Brain and mental healthSingle-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for Nrgn and Sgk1 in response to a social stressor
Topic: Brain and mental healthBrain Region-Specific Oligodendrocyte States Highlight Mitochondrial Gene Upregulation and Loss of Canonical Identity Signatures in Alzheimer’s Disease
Topic: Immunity and inflammationA combinatorial transcription factor screening platform for immune cell reprogramming
Topic: Immunity and inflammationMultimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers
Topic: Cell fate and dynamicsProtocol for Predicting Cell Fate Responses to in Silico Perturbation using RegVelo, from Code to Agentic Platform Analysis
202558 publications
Topic: Open-source softwarePertpy: an end-to-end framework for perturbation analysis
Topic: Immunity and inflammationA single-cell cytokine dictionary of human peripheral blood
Topic: Single-cell genomicsDISCO-seq: 3D single-cell transcriptomics of intact biological systems
Topic: Spatial omicsExploration of RNA outside segmented cells in spatial transcriptomics reveals extrasomatic RNA organization
Topic: Cell fate and dynamicsPseudodynamics+: Reconstructing Population Dynamics from Time-Resolved Single Cell Landscapes with Physics Informed Neural Networks
Topic: Deep learning and generative modelsActive learning framework leveraging transcriptomics identifies modulators of disease phenotypes
Topic: Open-source softwareOmniPath: integrated knowledgebase for multi-omics analysis
Topic: Open-source softwareQuiCAT: a scalable and flexible framework for mapping synthetic sequences
Topic: Deep learning and generative modelsLanguage may be all omics needs: Harmonizing multimodal data for omics understanding with CellHermes
Topic: Cell atlasesSpatial single-cell atlas reveals regional variations in healthy and diseased human lung
Topic: Data integrationFADVI: disentangled representation learning for robust integration of single-cell and spatial omics data
Topic: Immunity and inflammationToward a ToxAtlas of Carbon-Based Nanomaterials: Single-Cell RNA Sequencing Reveals Initiating Cell Circuits in Pulmonary Inflammation
Topic: Deep learning and generative modelsNicheformer: a foundation model for single-cell and spatial omics
Topic: Data integrationIntegrating single-cell RNA-seq datasets with substantial batch effects
Topic: Spatial omicsNicheFlow - Data, Checkpoints, and Results
Topic: Cell fate and dynamicsA multimodal cross-species comparison of pancreas development
Topic: Gene regulationscooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution
Topic: Single-cell genomicsMapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Topic: Cell fate and dynamicsDisentangling Transcription Factor Programs for Direct Reprogramming with Generative Modeling
Topic: Deep learning and generative modelsscConcept: Contrastive pretraining for technology-agnostic single-cell representations beyond reconstruction
Topic: Spatial omicsAdvancing spatial biology analysis across programming languages
Topic: Deep learning and generative modelsGraph neural networks learn emergent tissue properties from spatial molecular profiles
Topic: ImagingscPortrait integrates single-cell images into multimodal modeling
Topic: Gene regulationSingle-cell multiome and spatial profiling reveals pancreas cell type–specific gene regulatory programs of type 1 diabetes progression
Topic: ImagingIm-seq: Multimodal droplet barcoding enables high-throughput linking of single-cell imaging and gene expression
Topic: Spatial omicsIntegration of cell-type resolved spatial proteomics and transcriptomics reveals novel mechanisms in early ovarian cancer
Topic: Spatial omicsSpatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
Topic: Single-cell genomicsSingle cell decomposition of multicellular aging programs associated with impaired lung regeneration
Topic: Deep learning and generative modelsA foundation model to predict and capture human cognition
Topic: Benchmarks and best practicesSpatial transcriptomics deconvolution methods generalize well to spatial chromatin accessibility data
Topic: Benchmarks and best practicesDefining and benchmarking open problems in single-cell analysis
Topic: Benchmarks and best practicesBeyond Visual Inspection: Principled Benchmarking of Single-Cell Trajectory Representations with scTRAM
Topic: Data integrationBiologically Informed Variational Inference Enables Interpretable Cell Phenotyping and Discovery
Topic: Cell atlasesAutomated evaluation of single-cell reference atlas mappings enables the identification of disease-associated cell states
Topic: Cell atlasesCharting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap
Topic: Cell atlasesAn integrated transcriptomic cell atlas of human endoderm-derived organoids
Topic: Metabolism and diabetesGIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice
Topic: Brain and mental healthExon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
Topic: Perturbation responsesCellFlow enables generative single-cell phenotype modeling with flow matching
Topic: Deep learning and generative modelsTowards multimodal foundation models in molecular cell biology
Topic: Brain and mental healthStress in the ventral hippocampus under single-cell resolution
Topic: Single-cell genomicsCausal machine learning for single-cell genomics
Topic: Deep learning and generative modelsUniversalEPI: a generalized attention-based deep ensemble model to accurately predict enhancer-promoter interactions across diverse cell types and conditions
Topic: Deep learning and generative modelsQuantitative characterization of cell niches in spatially resolved omics data
Topic: Benchmarks and best practicestheislab/atlas-feature-selection-benchmark: 2025-03-15: Publication
Topic: Benchmarks and best practicesOptimizing Xenium In Situ data utility by quality assessment and best-practice analysis workflows
Topic: Benchmarks and best practicesFeature selection methods affect the performance of scRNA-seq data integration and querying
Topic: Deep learning and generative modelsTransformers and genome language models
Topic: Single-cell genomicsBiases in machine-learning models of human single-cell data
Topic: Cell fate and dynamicsTGIF2 is a major regulator of neural stem cell fate and neurogenic priming
Topic: Brain and mental healthChronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids
Topic: Metabolism and diabetesSpatial profiling of human pancreas during type 1 diabetes progression
Topic: Spatial omicsWhat is the main bottleneck in deriving biological understanding from spatial transcriptomic profiling?
Topic: Deep learning and generative modelsUnified Guidance for Geometry-Conditioned Molecular Generation
Topic: Single-cell genomicsMapping cells through time and space with moscot
Topic: ImagingPredicting cell morphological responses to perturbations using generative modeling
TarDis: Achieving Robust and Structured Disentanglement of Multiple Covariates
Topic: Benchmarks and best practicesData for "Feature selection methods affect the performance of scRNA-seq data integration and querying"
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