Publications
Publications of 2023
The works of 2023 by the lab's members during their time here, from their ORCID records, Crossref and Europe PMC.
51 publications9 preprintsLater: 2024Earlier: 2022All publications
202351 publications
Topic: Benchmarks and best practices Topic: ImagingDeep Learning-Based Retinal Layer Segmentation in Optical Coherence Tomography Scans of Patients with Inherited Retinal Diseases
Topic: Clinical and cohort dataExploratory electronic health record analysis with ehrapy
Topic: Perturbation responsesEx vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis
Topic: Single-cell genomicsModeling fragment counts improves single-cell ATAC-seq analysis
Topic: Brain and mental healthEarly life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus
Topic: ImagingExplainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies
Topic: Brain and mental healthA reversible state of hypometabolism in a human cellular model of sporadic Parkinson’s disease
Topic: Data integrationflowVI: Flow Cytometry Variational Inference
Reporting electricity consumption is essential for sustainable AI
Topic: Cell fate and dynamicsHuman pluripotent stem cell fate trajectories toward lung and hepatocyte progenitors
Topic: Clinical and cohort dataReconstructing disease dynamics for mechanistic insights and clinical benefit
Topic: Deep learning and generative modelsScaling cross-tissue single-cell annotation models
Topic: Data integrationPopulation-level integration of single-cell datasets enables multi-scale analysis across samples
Topic: Single-cell genomicsSingle-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment
Topic: Perturbation responsesSystematic analysis of drug combinations against Gram-positive bacteria
Topic: Cell fate and dynamicsDeep generative modeling of transcriptional dynamics for RNA velocity analysis in single cells
Topic: Single-cell genomicsIdentification of cell types, states and programs by learning gene set representations
Topic: Cell atlasesDelineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas
Topic: Perturbation responsesEx vivo tissue perturbations coupled to single-cell RNA-seq reveal multi-lineage cell circuit dynamics in human lung fibrogenesis
Topic: Spatial omicsA spatially resolved extracellular matrix proteome atlas of the distal human lung
Topic: Networks and graphsMulti-omics regulatory network inference in the presence of missing data
Topic: Single-cell genomicsRobust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel
Topic: Immunity and inflammationDistinct molecular profiles of skull bone marrow in health and neurological disorders
Topic: Cell fate and dynamicsProgressive disruption of hematopoietic architecture from clonal hematopoiesis to MDS
Topic: Immunity and inflammationThe neglected twin: Nummular eczema is a variant of atopic dermatitis with codominant TH2/TH17 immune response
Topic: Immunity and inflammationGene Expression–Based Molecular Test as Diagnostic Aid for the Differential Diagnosis of Psoriasis and Eczema in Formalin-Fixed and Paraffin-Embedded Tissue, Microbiopsies, and Tape Strips
Topic: Single-cell genomicshadge: a comprehensive pipeline for donor deconvolution in single cell
Topic: Cell fate and dynamicsUnified fate mapping in multiview single-cell data
Topic: Bulk omics and geneticsTolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
Topic: ImagingOME-Zarr: a cloud-optimized bioimaging file format with international community support
Topic: Deep learning and generative modelsscARE: Attribution Regularization for Single Cell Representation Learning
Topic: Cell atlasesSingle-cell reference mapping to construct and extend cell-type hierarchies
Topic: Perturbation responsesLongitudinal Effects of 1-Year Smoking Cessation on Human Bronchial Epithelial Transcriptome
Topic: Single-cell genomicsSingle‐cell biology: what does the future hold?
Topic: Single-cell genomicsCIARA: a cluster-independent algorithm for identifying markers of rare cell types from single-cell sequencing data
Topic: Immunity and inflammationSystemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease
Topic: Spatial omicsWhat do you most hope spatial molecular profiling will help us understand? Part 1
Topic: Cell atlasesAn integrated cell atlas of the lung in health and disease
Topic: Immunity and inflammation394 Gene expression based molecular test proves clinical validity as diagnostic aid for the differential diagnosis of psoriasis and eczema in formalin fixed and paraffin embedded tissue
Topic: Deep learning and generative modelsLearning consistent subcellular landmarks to quantify changes in multiplexed protein maps
Topic: Deep learning and generative modelsDeciphering subcellular organization with multiplexed imaging and deep learning
Topic: Perturbation responsesPredicting cellular responses to complex perturbations in high‐throughput screens
Topic: Single-cell genomicsThe scverse project provides a computational ecosystem for single-cell omics data analysis
Topic: Cell fate and dynamicsEpicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease
Topic: Benchmarks and best practicesBest practices for single-cell analysis across modalities
Topic: Single-cell genomicsSingle-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy
Topic: Immunity and inflammationSynthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy
Topic: Bulk omics and geneticsHBV rewires liver cancer signaling by altering PP2A complexes
Topic: Deep learning and generative modelsBiologically informed deep learning to query gene programs in single-cell atlases
Topic: Deep learning and generative modelsB-Cos Aligned Transformers Learn Human-Interpretable Features