Publications
Publications of 2018
The works of 2018 by the lab's members during their time here, from their ORCID records, Crossref and Europe PMC.
32 publications3 preprintsLater: 2019Earlier: 2017All publications
201832 publications
Topic: Single-cell genomics Topic: Mechanistic modellingMulti-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection
Topic: Brain and mental healthIncreasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis
Topic: Mechanistic modellingEfficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model
Topic: Mechanistic modellingMechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data
Topic: Deep learning and generative modelsGenerative modeling and latent space arithmetics predict single-cell perturbation response across cell types, studies and species
Topic: Cell fate and dynamicsData Driven Computational Modeling of Hematopoiesis in Myelodysplastic Syndromes Unveils Differences in Hematopoietic Stem Cell Kinetics Compared to Age-Matched Healthy Controls
Topic: Open-source softwareIRkernel: Native R Kernel for the 'Jupyter Notebook'
Topic: Metabolism and diabetesImpact of Brain Fatty Acid Signaling on Peripheral Insulin Action in Mice
Topic: Benchmarks and best practicesCopy number aberrations from Affymetrix SNP 6.0 genotyping data—how accurate are commonly used prediction approaches?
Topic: Open-source softwareMetaMap, an interactive webtool for the exploration of metatranscriptomic reads in human disease-related RNA-seq data
Topic: Cell fate and dynamicsMetabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate
Topic: Benchmarks and best practicesCharacterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies
Topic: Statistical inferenceImpulse model-based differential expression analysis of time course sequencing data
Topic: Immunity and inflammationType I Immune Response Induces Keratinocyte Necroptosis and Is Associated with Interface Dermatitis
Topic: Cell fate and dynamicsLineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm
Topic: Immunity and inflammationIs the humoral immunity dispensable for the pathogenesis of psoriasis?
Topic: Perturbation responsesInductive and Selective Effects of GSK3 and MEK Inhibition on Nanog Heterogeneity in Embryonic Stem Cells
Topic: Statistical inferenceBayesian parameter estimation for biochemical reaction networks using region-based adaptive parallel tempering
Topic: Open-source softwareMetaMap: an atlas of metatranscriptomic reads in human disease-related RNA-seq data
Topic: Immunity and inflammationThe role of humoral immunity in the pathogenesis of psoriasis
Topic: Cell fate and dynamicsCell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics
Topic: Immunity and inflammationMathematical concepts and their challenges in predicting severity of atopic eczema patients
Topic: Immunity and inflammationToll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects
Topic: Immunity and inflammationEarly Identification of Bronchopulmonary Dysplasia Using Novel Biomarkers by Proteomic Screening
Topic: Open-source softwareFASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
Topic: Gene regulationEpigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients
Whither systems medicine?
Topic: Open-source softwareSCANPY: large-scale single-cell gene expression data analysis
Topic: Metabolism and diabetesMaternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin
Topic: Perturbation responsesLifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk
LNA++: Linear Noise Approximation with First and Second Order Sensitivities