Plate IV.85 · Publications

A foundation model to predict and capture human cognition

Article in Nature, 2 July 2025.

Open accessResearch area: Representations, Single Cell

Authors

  1. Marcel Binz
  2. Elif Akata
  3. Matthias Bethge
  4. Franziska Brändle
  5. Fred Callaway
  6. Julian Coda-Forno
  7. Peter Dayan
  8. Can Demircan
  9. Maria K. Eckstein
  10. Noémi Éltető
  11. Thomas L. Griffiths
  12. Susanne Haridi
  13. Akshay K. Jagadish
  14. Li Ji-An
  15. Alexander Kipnis
  16. Sreejan Kumar
  17. Tobias Ludwig
  18. Marvin Mathony
  19. Marcelo Mattar
  20. Alireza Modirshanechi
  21. Surabhi S. Nath
  22. Joshua C. Peterson
  23. Milena Rmus
  24. Evan M. Russek
  25. Tankred Saanum
  26. Johannes A. Schubert
  27. Luca M. Schulze Buschoff
  28. Nishad Singhi
  29. Xin Sui
  30. Mirko Thalmann
  31. Fabian J. Theis
  32. Vuong Truong
  33. Vishaal Udandarao
  34. Konstantinos Voudouris
  35. Robert Wilson
  36. Kristin Witte
  37. Shuchen Wu
  38. Dirk U. Wulff
  39. Huadong Xiong
  40. Eric Schulz

Abstract

Establishing a unified theory of cognition has been an important goal in psychology1,2. A first step towards such a theory is to create a computational model that can predict human behaviour in a wide range of settings. Here we introduce Centaur, a computational model that can predict and simulate human behaviour in any experiment expressible in natural language. We derived Centaur by fine-tuning a state-of-the-art language model on a large-scale dataset called Psych-101. Psych-101 has an unprecedented scale, covering trial-by-trial data from more than 60,000 participants performing in excess of 10,000,000 choices in 160 experiments. Centaur not only captures the behaviour of held-out participants better than existing cognitive models, but it also generalizes to previously unseen cover stories, structural task modifications and entirely new domains. Furthermore, the model's internal representations become more aligned with human neural activity after fine-tuning. Taken together, our results demonstrate that it is possible to discover computational models that capture human behaviour across a wide range of domains. We believe that such models provide tremendous potential for guiding the development of cognitive theories, and we present a case study to demonstrate this.

Cite

@article{binz2025foundation,
  title = {{A foundation model to predict and capture human cognition}},
  author = {Binz, Marcel and Akata, Elif and Bethge, Matthias and Brändle, Franziska and Callaway, Fred and Coda-Forno, Julian and Dayan, Peter and Demircan, Can and Eckstein, Maria K. and Éltető, Noémi and Griffiths, Thomas L. and Haridi, Susanne and Jagadish, Akshay K. and Ji-An, Li and Kipnis, Alexander and Kumar, Sreejan and Ludwig, Tobias and Mathony, Marvin and Mattar, Marcelo and Modirshanechi, Alireza and Nath, Surabhi S. and Peterson, Joshua C. and Rmus, Milena and Russek, Evan M. and Saanum, Tankred and Schubert, Johannes A. and Schulze Buschoff, Luca M. and Singhi, Nishad and Sui, Xin and Thalmann, Mirko and Theis, Fabian J. and Truong, Vuong and Udandarao, Vishaal and Voudouris, Konstantinos and Wilson, Robert and Witte, Kristin and Wu, Shuchen and Wulff, Dirk U. and Xiong, Huadong and Schulz, Eric},
  journal = {Nature},
  publisher = {Springer Science and Business Media LLC},
  year = {2025},
  month = jul,
  doi = {10.1038/s41586-025-09215-4},
  url = {https://doi.org/10.1038/s41586-025-09215-4},
  pmid = {40604288},
  pmcid = {PMC12390832}
}
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