Publications
Publications of 2021
The works of 2021 by the lab's members during their time here, from their ORCID records, Crossref and Europe PMC.
41 publications5 preprintsLater: 2022Earlier: 2020All publications
202141 publications
Topic: Immunity and inflammation Topic: Benchmarks and best practicesBenchmarking atlas-level data integration in single-cell genomics
Topic: Immunity and inflammationSARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis
Topic: Single-cell genomicsGraph representation learning for single-cell biology
Topic: Metabolism and diabetesVertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes
Topic: Statistical inferencescCODA is a Bayesian model for compositional single-cell data analysis
Topic: Single-cell genomicsscPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies
Topic: Gene regulationDeterminants of expression of SARS‐CoV‐2 entry‐related genes in upper and lower airways
Topic: Single-cell genomicsOver 1000 tools reveal trends in the single-cell RNA-seq analysis landscape
A field guide to cultivating computational biology
Topic: Metabolism and diabetesKünstliche Intelligenz und maschinelles Lernen in der Diabetesforschung
Topic: Bulk omics and geneticsCurrent Smoking Alters Gene Expression and DNA Methylation in the Nasal Epithelium of Patients with Asthma
Topic: Metabolism and diabetesDiet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice
Topic: Immunity and inflammationAged alveolar epithelium contributes to inflammaging and reduced stem cell function in the lung
Topic: Perturbation responsesChronic WNT/ß-catenin signaling impairs mitochondrial function in lung epithelial cells
Topic: Deep learning and generative modelsOut-of-distribution prediction with disentangled representations for single-cell RNA sequencing data
Topic: Single-cell genomicsEpiScanpy: integrated single-cell epigenomic analysis
Topic: Cell atlasesMapping single-cell data to reference atlases by transfer learning
Topic: Single-cell genomicsSfaira accelerates data and model reuse in single cell genomics
Topic: Immunity and inflammationGroup Testing for SARS-CoV-2 Allows for Up to 10-Fold Efficiency Increase Across Realistic Scenarios and Testing Strategies
Topic: Cell fate and dynamicsRNA velocity—current challenges and future perspectives
Topic: Immunity and inflammationSingle-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’
Topic: Bulk omics and geneticsAutoGeneS: Automatic gene selection using multi-objective optimization for RNA-seq deconvolution
Topic: Metabolism and diabetesCD81 marks immature and dedifferentiated pancreatic β-cells
Topic: Cell fate and dynamicsEpithelial cell plasticity drives endoderm formation during gastrulation
Topic: Immunity and inflammationLow numbers of cytokine transcripts drive inflammatory skin diseases by initiating amplification cascades in localized epidermal clusters
Topic: Perturbation responsesMachine learning for perturbational single-cell omics
Topic: Bulk omics and geneticsSwarm Learning for decentralized and confidential clinical machine learning
Topic: Brain and mental healthCellular connectomes as arbiters of local circuit models in the cerebral cortex
Topic: Bulk omics and geneticsComparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?
Topic: Metabolism and diabetesAsc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population
Topic: Data integrationIntegrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Topic: Open-source softwareIntegrated intra‐ and intercellular signaling knowledge for multicellular omics analysis
Topic: Immunity and inflammationCD23 Levels on B Cells Determine Long-Term Therapeutic Response in Patients with Atopic Eczema Treated with Selective IgE Immune Apheresis
Topic: Perturbation responsesPosterior subcapsular cataracts are a late effect after acute exposure to 0.5 Gy ionizing radiation in mice
Topic: Cell fate and dynamicsSingle cell trajectory analysis of human pluripotent stem cells differentiating towards lung and hepatocyte progenitors
Topic: Spatial omicsSquidpy: a scalable framework for spatial single cell analysis
Topic: Deep learning and generative modelsDeep learning the collisional cross sections of the peptide universe from a million experimental values
Topic: Clinical and cohort dataDeep Learning-based Propensity Scores for Confounding Control in Comparative Effectiveness Research
Topic: Single-cell genomicsSingle-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation
Topic: Cell fate and dynamicsNon-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates