Pretty, but more snow here at Breckenridge 😝
View on X: post of 16 Jan 2019View towards the Alps from our new Helmholtz Diabetes Center in Munich! Just moved in a few months ago, but really broaden one‘s horizon :-)
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Plate VI · News
Posts on X
New papers, tools and news, as posted by @fabian_theis. Replies and reposts are left out.
Thx, Christopher, valid point - we should include that in SI. We compared to some other potential latent space approaches as you maybe saw.
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View on X: post of 16 Jan 2019@BartDeplancke reviving the 70s: his DisCo (deterministic co-encapsulation) method aims to improve droplet sequencing by avoiding incomplete droplets using computer vision. Fun fact: his group working on that is the Techno team. #KSsinglecell
View on X: post of 16 Jan 2019Mind-blowing talk by @priscaliberali at #KSsinglecell measuring >500k intestinal organoids and quantifying heterogeneity during their development - amongst others using pseudotemporal ordering, originally developed for single-cell data.
View on X: post of 16 Jan 2019Plus, they miss out on so much. Nobody later says ‚I should have worked more‘
View on X: post of 16 Jan 2019I found a useful heuristic: avoid working with people who don’t take an active part in their childrens’ lives but pride themselves on how they farm out all of this to their partners. More likely than not they’re unpleasant and selfish to work with.
Quoted postWelcome to the dark side :)
View on X: post of 16 Jan 2019The cat is out of the bag: the lab’s first deep learning paper (by #MahsaGhanbari), my first neural network paper in more than 15 years... Deep neural networks for interpreting RNA binding protein target preferences biorxiv.org/content/early/…
Quoted postHey, need good annotation for training ;)
View on X: post of 16 Jan 2019Comp Bio Open panel discussion: What are the major upcoming challenges? @fabian_theis: Annotation. Said no ML modeler ever ;-) #KSsinglecell
Quoted postGood point - this could only work if the algorithm has been exposed to intersubject variation during training. Worthwhile trying out and at the same time example that calls for some metric to evaluate prediction/imputation. #KSsinglecell
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View on X: post of 16 Jan 2019Looking forward to contributing to this future platform for molecular health research focusing on #singlecell techniques.
View on X: post of 16 Jan 2019Great news on @LifeTimeFET project! For Helmholtz Munich the scientists Maria Elena Torres-Padilla and @fabian_theis participate in this great project.
Quoted postHonored to be on panel discussion today about future of #singlecell #compbio, with @dana_peer, Rahul @satijalab and Allon Klein. Suggestions were integration with previous data sets and across omics layers, include real time and potentially learn more mechanistic models.
View on X: post of 15 Jan 2019Great keynote by Scott Fraser on new multimodal microscopy tools, speedup being a big topic. Although I have a hunch that his statement that "any time multiplied by 10^9 is a long time" may not hold. #KSsinglecell
View on X: post of 14 Jan 2019Excited to talk at the Keystone meeting on Single Cell Biology (hosted by Bertie Göttgens and Timm Schroeder) starting now @Breckenridge. 400 people, fully booked, wow. #KSsinglecell
View on X: post of 14 Jan 2019Excited that our paper on batch effect quantification in single-cell RNA-seq is finally out - thanks @marenbuettner and Chichau for taking the lead on this. Great collaboration with Teichmann lab @sangerinstitute. rdcu.be/bd13g
View on X: post of 21 Dec 2018
Congratulations Mireya and all of @N_Rajewsky lab!
View on X: post of 21 Dec 2018Never thought that my research would be among the breakthroughs of the year! Thanks @solana_jordi @falexwolf @sayoub_bln @PetarGlazar Benedikt Obermayer @fabian_theis Christine Kocks @N_Rajewsky for all the work! vis.sciencemag.org/breakthrough20…
Quoted postInterested in doing a PhD in data science? Please consider applying for our new grad school!
View on X: post of 20 Dec 2018We are delighted to announce the first call for applications to join the newly established Munich School for Data Science (MUDS). Please spread this info and encourage candidates to apply. More info on mu-ds.de #DataScience #phd
Quoted postHad this on mine as well (clogged or so, known issue) - hammering the key a bit when holding the laptop vertically actually did help...
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View on X: post of 19 Dec 2018Thanks for visiting, Denis - really enjoyed the discussion today!
View on X: post of 17 Dec 2018On my way to @ICBmunich to talk about the metastatic melanoma ecosystem during RAF/MEK inhibition in patients combining @histoCAT and #CyCIF. Thank you for this great opportunity! helmholtz-muenchen.de/icb/institute/…
Quoted postThat‘s exactly how I feel compiling my family‘s foto library at the end of each year.
View on X: post of 17 Dec 2018History Department xkcd.com/2086/ m.xkcd.com/2086/
Quoted postTransferring reviews, really like the idea.
View on X: post of 17 Dec 2018Tackling waste in publishing through portable peer review preview-bmcbiol.biomedcentral.com/articles/10.11…
Quoted postA bit short on results but I liked ‚I am the only subject in this study and I gave my informed consent.‘
View on X: post of 17 Dec 2018OK, 2018 can't end soon enough. Some French high school student translated a part of the Bible and Koran into protein sequence, made an rAAV vector and a cyclic peptide, injected them into either thigh, and then published the following preprint: osf.io/yj8xw/
Quoted postMontezuma’s Revenge, my first adventure game, has been solved by a new method for hard-exploration problems. Authors claim to have tackled the 'detachment problem' in 'intrinsic motivation' algorithms. Gotta love those #DeepLearning metaphors. eng.uber.com/go-explore
View on X: post of 11 Dec 2018
Just read about "AI peer reviewers" - let's build a sample database of its reviews and then build another AI to write the optimal papers; fun GAN problem nature.com/articles/d4158…
View on X: post of 6 Dec 2018Cool tool, beautifully summarized!
View on X: post of 6 Dec 2018The first paper from our lab is finally out! Single-cell mapping of lineage and identity in direct reprogramming: nature.com/articles/s4158… @nature Thread.. (spoiler alert: all our tools, protocols and data are freely available)
Quoted postLOVE it - will never be able to sing jingle bells now without a smile, or slip of the tongue 😂❄️🔔
View on X: post of 5 Dec 2018Poke @fabian_theis
Quoted postWelcome, Michael, excited to work together!
View on X: post of 5 Dec 2018Join our new Research Group ‘Computational Biomedicine’ launched on the 1st of February 2019 and headed by @MendenMichael .We are searching for PhD candidates: bit.ly/2B1WyO7 and Postdoc candidates: bit.ly/2G2uQqd .
Quoted postLooking forward to the Bioconductor meeting tomorrow!
View on X: post of 5 Dec 2018Happy to host the European Bioconductor meeting in Munich #EuroBioc2018. 100+ participants and a wide range of biostats, omics data analysis, visualization… Looking forward to tomorrow! bioconductor.github.io/EuroBioc2018/
Quoted postInteresting study - electric cars will cost Germany 100k jobs by 2035, many highly qualified ones. Students, please consider data engineering instead of automotive engineering. #dataNotCars spon.de/afne7 @SPIEGELONLINE
View on X: post of 5 Dec 2018
