Posts on X

Exciting talk today by @ThomasFuchsAI at our #ICBLunchtime Seminar about his work in computational pathology. We then discussed about AI's potential to democratize health care - current state: "the future is already here but it's just not even distributed" (William Gibson) - true

Exciting day for comp bio & ML, with AlphaFold and RoseTTAFold both out today @Nature and @ScienceMagazine, resp. Great work, but I prefer Rosetta's conclusion: "We make the method available to the scientific community". 🤓 nature.com/articles/s4158… science.sciencemag.org/content/early/…

Happy to share our recent preprint on leveraging graph neural networks for spatial omics: @davidsebfischer & @AnnaCSchaar introduce node-centric expression models (NCEMs), which learn single cell communication of tissue niches from spatial profiling data. biorxiv.org/content/10.110…

@AntoineBordes @facebookai talking about what's next for AI/ML. I buy into the application part on humanit's challenges. Any other thoughts?

@humancellatlas general meeting starting now, with Aviv Regev and Sarah Teichmann reviewing current state. Really impressed, happy and proud with the project being truly international and widely active! Join the 3day meeting at gm2021.humancellatlas.org

@ERC_Research bars Switzerland from applying for European research grants - this is clearly bad for the European science landscape. Genova colleague Y Flückinger says "research is hostage to a political game", indeed... sciencebusiness.net/news/eu-bars-s…

@UEFA 🏳️‍🌈 Everything is politics. (Thomas Mann)

Can we model a cell's response to perturbations/drugs via single-cell omics? In our perspective @CellSystemsCP, led by @_yji_ , we categorize related objectives, review recent machine learning approaches and then examine future avenues via deep learning. cell.com/cell-systems/f…

Really happy that our bulk deconvolution method AutoGeneS is now out in @CellSystemsCP! @AlieeHana developed a multi-objective gene selection method to use reference profiles from single-cell data for finding more in big bulk cohorts. sciencedirect.com/science/articl…

Interested in space, relativistic physics, microbiology, evolution or rockets? Please stop any science you’re currently doing and read @andyweirauthor‘s new book ‚Project Hail Mary‘ now - just finished it, and absolutely loved it! 🚀 🪐🦠👾👽👩‍🚀🧫📖

Preeeetty sweet @Nature cover from @LabSchultze on the swarm learning story for decentralized and confidential clinical machine learning! nature.com/articles/s4158…

Reviewer's troubles: "Many citations are not peer-viewed publications, so the supporting evidence in current manuscript is weak." What would you answer?

Dear Science-Twitter, with many of us planning to move back to offices at least in part, how would you recommend to do 'mixed-reality' meetings and talks? Any recomendation wrt tools/hardware/software/best-practices or links to similar discussions would be greatly appreciated!

Looking forward to our #ISMBECCB special session on "Single-cell and Spatial Data Analysis", with great keynotes from @teichlab, @morris_lab, @drjosephpowell & Zemin Zhang. Please join and/or submit abstract until May 31st! iscb.org/ismbeccb2021-p… @ISCB

Seeking a postdoc with expertise in machine learning to work on exciting methods for representation learning in single cell genomics. Please apply here: jobs.helmholtz-muenchen.de/jobposting/0cf… @HelmholtzMunich #postdocjobs

@CSHL #BoG21 Development & single cell genomics session starting now. Great intro by Nicole King on hypotheses on the origin of animals; now single cell analysis of genetic control in immune cells by Jose Alquicira-Hernandez. And: check out the cool mission control screen @CSHL!

Caroline Uhler of @MIT giving advice on successful interdisciplinary interactions: be humble. #ICLR2021

Great and really fun panel discussion at #ICLR2021 workshop on high impact applications of geometric representation learning. And supernice gathertown website for talk and poster viewing!

Stunning talk by Özlem Türeci @BioNTech_Group at our @HelmholtzMunich townhall meeting, describing their #covid19 vaccine development in only 10 months, now administered to 260M people - what a success story!

Sitting in a talk with this intro slide - what do you think this is about?

Interested in researching machine learning in Munich? @helmholtz_ai and @TU_Muenchen are looking to jointly hire two assistant/associate/full professors, one for algorithmic ML & explainable AI, one for data integration. Apply now! bit.ly/HelmholtzAI_al… bit.ly/HelmholtzAI_DI…

Excited to share 'compositional perturbation autoencoder', our new tool for single-cell response modeling. Led by @MohammadLotfol1 & @AKlimovskaia @FacebookAI, we combine interpretability of linear models with flexibility of DL. biorxiv.org/content/10.110… ai.facebook.com/blog/ai-predic…

Bernt Schiele talking at @helmholtz_ai conference on functionality stealing - interesting for learning with little information, important for many applications. arxiv.org/abs/1812.02766 #HelmholtzAIcon

@dana_peer kicking off @cziscience's Seed Network Comp Bio workshop (great lineup!) talking about single cell atlases & integration challenges: "An atlas is more than a UMAP with labels", yeah! Great summary of questions + tasks needed to be tackled by computational methods!

AI for drug discovery - is it becoming a reality or still hype? Interesting but tough take on the subject by @mostafabenh. Not sure I agree with all but would be great to see some papers out of startups/cps such as @insitro and others. melwy.com/blog/ai-for-dr…

Interesting outlook @NatureBiotech towards the next 25 years of biotech, which "must put people at its center" - not only for precision therapy but also regarding "equity, ethics, dialogue and social responsibility", needed for broad dissemination. Agreed! nature.com/articles/s4158…

#Europe is an awesome idea, with some implementation issues now and then. I want environmental & digital rights etc 👉exciting new initiative from F Schirach and others for new fundamental rights in #Europe. Please RT/consider signing the petition! 👩‍⚖️🇪🇺you.wemove.eu/campaigns/for-…

Omnipath @JulioSaezRod lab just out in @MolSystBiol: it integrates over 100 resources for a knowledge base of intra‐& inter‐cellular signaling. Really useful for single-cell omics, eg for greatly extended CellPhoneDB interactions. embopress.org/doi/full/10.15… omnipathdb.org

Interesting interview with Aviv Regev about her move to @genentech: How to deliver better medicine? 1. human biology, 2. high-res methods, 3. modalities, and 4. computation & maths, the latter for "predictive, generative and interpretable models". nature.com/articles/d4157…

Wondering why we can‘t get any work done anymore properly? According to Cal Newport, we live in a ‚hyperactive hive mind‘, with #slack, #twitter and plain old #email killing any concentration. His recommendation: minimize asynchronous communication. 🤔 wsj.com/articles/a-wor…