Plate IV.630 · Publications

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes

Article in Genome Biology, 20 January 2010.

Open accessResearch area: miRNA, Target, Cancer

Authors

  1. Andreas Ruepp
  2. Andreas Kowarsch
  3. Daniel Schmidl
  4. Felix Buggenthin
  5. Barbara Brauner
  6. Irmtraud Dunger
  7. Gisela Fobo
  8. Goar Frishman
  9. Corinna Montrone
  10. Fabian J Theis

Abstract

In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.

Cite

@article{ruepp2010phenomir,
  title = {{PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes}},
  author = {Ruepp, Andreas and Kowarsch, Andreas and Schmidl, Daniel and Buggenthin, Felix and Brauner, Barbara and Dunger, Irmtraud and Fobo, Gisela and Frishman, Goar and Montrone, Corinna and Theis, Fabian J},
  journal = {Genome Biology},
  publisher = {Springer Science and Business Media LLC},
  year = {2010},
  month = jan,
  doi = {10.1186/gb-2010-11-1-r6},
  url = {https://doi.org/10.1186/gb-2010-11-1-r6},
  pmid = {20089154},
  pmcid = {PMC2847718}
}
.bib file